Interesting article in NEJM last week.
77% survival rate among alcoholic hepatitis patients who got early liver transplants compared to 22% among those not receiving an early liver transplant. The NNT is 2… So we would need to treat 2 alcoholic hepatitis patients with early liver transplantation to save one life.
Obviously, there’s controversy in giving alcoholics liver transplants. Alcoholics usually have to be sober for 6 months to be considered for a liver transplant. Most alcoholics with severe hepatitis not responsive to therapy won’t survive the 6 months without a transplant. There isn’t any wait time for acetominophen-overdose liver transplants or from fatty liver. Should we be placing such a stigma on alcoholics that need a liver transplants vs. a person trying to commit suicide vs. an overweight person who continues to eat an unhealthy diet?
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