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Researchers  have long tied type 2 diabetes to chronic inflammation, caused by a  ramping-up of immune system activity that ultimately damages insulin  receptor signalling and leads to insulin resistance. But in September,  Umut Ozcan, an obesity researcher at Children’s Hospital Boston, reported that a key inflammatory protein actually reduces insulin resistance in obese diabetic mice, curing them of diabetes. The protein, called  XBP-1s, turns on genes that direct the assembly of other proteins that  keep insulin function working correctly in the cells.
Could be promising.
Side note: I can’t help but think those donuts in the stock photo look delicious.
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Researchers have long tied type 2 diabetes to chronic inflammation, caused by a ramping-up of immune system activity that ultimately damages insulin receptor signalling and leads to insulin resistance. But in September, Umut Ozcan, an obesity researcher at Children’s Hospital Boston, reported that a key inflammatory protein actually reduces insulin resistance in obese diabetic mice, curing them of diabetes. The protein, called XBP-1s, turns on genes that direct the assembly of other proteins that keep insulin function working correctly in the cells.

Could be promising.

Side note: I can’t help but think those donuts in the stock photo look delicious.

    • #diabetes
    • #XBP-1s
    • #inflammation
    • #Discover Magazine
  • 4 months ago
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Christine Chronicles

Avatar "Take the world apart and figure out how it works." - Built to Spill, 1994.

An internal medicine resident's journey through public health, island living, medical school, clerkship rotations, internship, residency and life...with many pit stops, detours and distractions along the way. This blog is a gallimaufry of stories, pictures, videos, things I like, things I see and things that catch my attention even if for a fleeting moment.

Feel free to contact me at:
christinechronicles@gmail.com
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